![]() This chapter will focus on the use of blood culture systems in the era of modern technology and aim to highlight the best practice from collection to interpretation of results. This method allows for microbial identification and susceptibility testing to be performed which is a critical component to managing sepsis, however the lack of rapid results and decreased sensitivity for fastidious pathogens has led to the development of improved systems and adjunctive molecular or proteomic testing.Ĭlinicians need to utilize their respective laboratories’ culturing systems optimally by adhering to the correct way of submitting blood culture specimens, understanding the principle of the testing method and making informed decisions regarding the results obtained. īlood cultures are still considered to be the ‘gold standard’ for the detection of microbial pathogens related to bacteraemia and sepsis despite newer molecular techniques. A recent multicentre retrospective evaluation has shown that more than 80% of bacteraemias and fungaemias occur within the hospital or other heathcare settings, with indwelling catheters being the most common source. Bacteraemia and sepsis is associated with a high mortality and an increased incidence of hospital stay and associated costs. ![]()
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